Outcomes and complications of combined heart-liver transplantation in patients with failing Fontan physiology: A systematic review

Table 5 Perioperative metrics and survival outcomes, median (range)/mean ± SD

Ref.	Population	ICU stay (days)	Hospital stay (days)	CPB time (minute)	RBC units	Ischemic time (minute)	30-day survival	1-year	5-year	10-year
Vaikunth et al[19] (2019)	40	23 (1–272)	38.5 (1–339)	316 (171–837)	21 (3–46)	231.5 (122–410)	36/40	32/40	30/40	30/40
Vaikunth et al[20] (2024)	9	19	36	260 (178–307)	22 (5–42)	280 (227–396)	9/9	9/9	N/A	N/A
Wu et al[18] (2024)	11	7.5 (5–11)	27.5 (17–33.5)	199 (158–261)	18 (6–26)	N/A	N/A	7/11	N/A	N/A
Sganga et al[21] (2021)	9	8 (6–19)	29 (16–42)	264 (243–327)	N/A	293 (255–336)	N/A	8/9	N/A	N/A
D’Souza et al[10] (2016)	7	N/A	29 (25–112)	218 (197–341)	N/A	211 (146–247)	N/A	7/7	N/A	N/A
Reardon et al[22] (2018)	5	N/A	51 (26–77)	260 (161–495)	N/A	181 (159–396)	5/5	5/5	5/5	5/5
Lewis et al[34] (2023)	40	30 ± 95.91	66 ± 124.58	310 ± 704.96	N/A	237 ± 1799.74	N/A	37/40	34/40	N/A
Aggregate	—	8.46 (4.66–12.25)	28.16 (19.56–36.76)	260.27 (227–293)	19.38 (8–30)	267.29 (227–307)	92.6%	86.8%	81.2%	77.8%

ICU: Intensive care unit; LOS: Length of stay; CPB: Cardiopulmonary bypass; N/A: Not applicable.