Current perspectives and guidelines on liver transplantation for metastatic colorectal cancer

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transplant. Dec 18, 2025; 15(4): 104945
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.104945

Table 1 Criteria for patients with colorectal metastatic cancer based on SECA I trial: Oslo score and Fong clinical risk score

Oslo score	Fong clinical risk score
Largest lesion diameter > 5.5 cm	Maximal lesion diameter > 5.0 cm
Pre-transplant CEA level > 80 μg/mL	Pre-resection CEA level > 200 μg/mL
Progression on chemotherapy	> 1 liver metastasis
Time from resection of the primary tumor to transplant < 24 months	Node-positive primary interval from diagnosis of primary to liver metastasis < 12 months

CEA: Carcinoembryonic antigen.

Citation: Stoyanova M, Mircheva I, Chulkov I, Karamiteva M, Goranova Z, Simeonova V, Zashev M, Velikova T, Peruhova M. Current perspectives and guidelines on liver transplantation for metastatic colorectal cancer. World J Transplant 2025; 15(4): 104945
URL: https://www.wjgnet.com/2220-3230/full/v15/i4/104945.htm
DOI: https://dx.doi.org/10.5500/wjt.v15.i4.104945

Stoyanova M, Mircheva I, Chulkov I, Karamiteva M, Goranova Z, Simeonova V, Zashev M, Velikova T, Peruhova M. Current perspectives and guidelines on liver transplantation for metastatic colorectal cancer. World J Transplant 2025; 15(4): 104945 [PMID: 41357396 DOI: 10.5500/wjt.v15.i4.104945]

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