©The Author(s) 2025.
World J Transplant. Dec 18, 2025; 15(4): 104589
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.104589
Published online Dec 18, 2025. doi: 10.5500/wjt.v15.i4.104589
Table 1 Definition of alcohol-associated hepatitis recommended by the National Institute on Alcohol Abuse and Alcoholism
| Items | |
| 1 | Onset of jaundice in the previous 8 weeks |
| 2 | Continuous alcohol consumption of > 40 (female) or > 60 (male) g/day for at least 6 months, with less than 60 days of abstinence before the onset of jaundice |
| 3 | Aspartate aminotransferase > 50, aspartate aminotransferase/alanine aminotransferase > 1.5, and both values less than 400 IU/L |
| 4 | Serum bilirubin (total) > 3.0 mg/dL |
| 5 | Liver biopsy confirmation in patients (macrovesicular steatosis, hepatocyte ballooning, and predominantly neutrophilic infiltration and Mallory-Denk bodies) |
| Exclusion of other liver disease (i.e., viral hepatitis, autoimmune liver diseases, Wilson disease, drug-induced liver injury, hepatocellular carcinoma) |
- Citation: Jung J, Hasjim BJ, Chen A, Hussain F, Rohan V, Ladner DP, Cheung A. Early liver transplant for alcohol-associated liver disease: Current state and future directions. World J Transplant 2025; 15(4): 104589
- URL: https://www.wjgnet.com/2220-3230/full/v15/i4/104589.htm
- DOI: https://dx.doi.org/10.5500/wjt.v15.i4.104589