Pediatric and adult liver transplantation in Bahrain: The experiences in a country with no available liver transplant facilities

doi:10.5500/wjt.v14.i1.87752

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Transplant. Mar 18, 2024; 14(1): 87752
Published online Mar 18, 2024. doi: 10.5500/wjt.v14.i1.87752

Table 6 Analysis of outcome in pediatric and adult liver transplantation

Variable	Survived, n = 141 (84.4)	Died, n = 26 (15.6)	P value
Sex			0.130^a
Male	85 (60.3)	11 (42.3)
Female	56 (39.7)	15 (57.7)
Nationality			0.471^a
Bahraini	127 (90.1)	25 (96.2)
Non-Bahraini	14 (9.9)	1 (3.8)
Area of residency			0.118^b
Northern	63 (44.7)	10 (38.5)
Capital	29 (20.6)	6 (23.1)
Southern	25 (17.7)	9 (34.6)
Muharraq	24 (17.0)	1 (3.8)
Age at liver transplant (yr)	48.8 (13.2-58.0)	57.5 (47.9-65.2)	0.019^c
Age group			0.346^a
Pediatric	42 (29.8)	5 (19.2)
Adult	99 (70.2)	21 (80.8)
Weight at transplant (kg), (n = 83)	52.0 (20.0-70.0)	8.0 (5.0-46.0)	0.144^c
Height at transplant (cm), (n = 76)	163.0 (149.0-169.0)	138.0 (74.0-149.0)	0.101^c
Presence of associated diseases	139 (98.6)	23 (88.5)	0.255^a
Yes	109 (78.4)	21 (91.3)
No	30 (21.6)	2 (8.7)
Type of graft (n = 150)	137 (97.2)	13 (50.0)	0.364^a
Living	122 (89.1)	13 (100)
Cadaveric	15 (10.9)	0 (0.0)
Donor-recipient relationship (n = 150)	137 (97.2)	13 (50.0)	0.704^a
Related donors	113 (82.5)	10 (76.9)
Unrelated donors	24 (17.5)	3 (23.1)
Indications of liver transplantation
Hepatitis C virus	37 (26.2)	5 (19.2)	0.623^a
Primary sclerosing cholangitis	18 (12.8)	2 (7.7)	0.743^a
Nonalcoholic steatohepatitis	15 (10.6)	4 (15.4)	0.503^a
Hepatic cellular carcinoma	14 (9.9)	6 (23.1)	0.092^a
Biliary atresia	13 (9.2)	3 (11.5)	0.718^a
Hepatitis B virus	13 (9.2)	2 (7.7)	1.000^a
Autoimmune hepatitis	11 (7.8)	1 (3.8)	0.694^a
Metabolic diseases	7 (5.0)	0 (0.0)	0.597^a
Intra- or post-LT complications (n = 150)	138 (97.9)	11 (42.3)	0.537^a
Yes	85 (61.6)	8 (72.7)
No	53 (38.4)	3 (27.7)
Post-LT N-acetylcysteine use	50/66 (75.8)	46/52 (88.5)	0.098
Liver transplant countries			0.582^b
Middle East	86 (61.0)	19 (73.1)
Asia & Pacific	51 (36.2)	8 (30.7)
Europe	4 (2.8)	0 (0.0)
North America	3 (2.1)	0 (0.0)
Follow-up duration (yr)	7.5 (3.9-10.6)	1.5 (0.3-3.2)	< 0.001^c

^aFisher’s exact test.

^bPearson’s χ² test.

^cMann-Whitney U test.

Data are presented as number and percentage or median and interquartile range. Boldface indicates a statistically significant difference with P < 0.05. LT: Liver transplantation.

Full Size Table

Citation: Isa HM, Alkharsi FA, Khamis JK, Hasan SA, Naser ZA, Mohamed ZN, Mohamed AM, Altamimi SA. Pediatric and adult liver transplantation in Bahrain: The experiences in a country with no available liver transplant facilities. World J Transplant 2024; 14(1): 87752
URL: https://www.wjgnet.com/2220-3230/full/v14/i1/87752.htm
DOI: https://dx.doi.org/10.5500/wjt.v14.i1.87752

Isa HM, Alkharsi FA, Khamis JK, Hasan SA, Naser ZA, Mohamed ZN, Mohamed AM, Altamimi SA. Pediatric and adult liver transplantation in Bahrain: The experiences in a country with no available liver transplant facilities. World J Transplant 2024; 14(1): 87752 [PMID: 38576753 DOI: 10.5500/wjt.v14.i1.87752]

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