Trends and outcomes of liver transplantation among older recipients in the United States

Table 3 Multivariable cox regression for five-year graft survival

Variables	B (SE)	Hazard ratio (95%CI)	P value
Year of transplant	-0.04 (0.002)	0.958 (0.955-0.961)	< 0.001
Age ≥ 65	0.24 (0.02)	1.27 (1.22-1.32)	< 0.001
Male	0.10 (0.02)	1.11 (1.08-1.14)	< 0.001
BMI (per10)	-0.05 (0.01)	0.95 (0.93-0.98)	0.001
Race			0.001
Caucasian	Ref	1.0 (Ref)
African American	0.23 (0.02)	1.26 (1.21-1.31)	< 0.001
Hispanic	-0.11 (0.02)	0.90 (0.86-0.94)	< 0.001
Asian	-0.21 (0.04)	0.81 (0.75-0.87)	< 0.001
Pre-LT diabetes	0.20 (0.02)	1.22 (1.18-1.26)	< 0.001
Ventilation	0.51 (0.03)	1.67 (1.59-1.76)	< 0.001
Pre-LT dialysis	0.20 (0.02)	1.23 (1.17-1.28)	< 0.001
Retransplant	0.44 (0.03)	1.55 (1.47-1.63)	< 0.001
PVT	0.21 (0.03)	1.23 (1.16-1.31)	< 0.001
R1-MELD (per 10)	0.04 (0.01)	1.05 (1.03-1.06)	< 0.001
HCV recipient	0.28 (0.01)	1.33 (1.29-1.36)	< 0.001
Donor race			< 0.001
Caucasian	Ref	1.0 (Ref)
African American	0.06 (0.02)	1.06 (1.02-1.10)	0.001
Hispanic	0.10 (0.02)	1.11 (1.06-1.16)	< 0.001
Asian	0.19 (0.04)	1.21 (1.11-1.31)	< 0.001
Donor risk index	0.34 (0.03)	1.41 (1.34-1.48)	< 0.001
Cold ischemia time	0.014(0.002)	1.014 (1.010-1.019)	< 0.001

¹Most recent.

BMI: Body mass index; LT: Liver transplantation; PVT: Portal vein thrombosis; CI: Confidence interval; HCV: Hepatitis C virus; MELD: Model for end-stage liver disease.