Post-transplant erythrocytosis after kidney transplantation: A review

Table 1 Post-transplant erythrocytosis management guidelines

Ref.	Society	Recommendations
KDIGO Transplant Work Group[11], 2009	KDIGO	Definition of erythrocytosis: hemoglobin > 17 g/dL or hematocrit > 51%. Recommend using ACE-Is or ARBs for initial treatment of erythrocytosis.
Bia et al[12], 2010	NKF/KDOQI	Recommend treatment when hemoglobin > 17-19 g/dL or hematocrit > 51%-52%. Treatment guidelines per 2009 KDIGO recommendations.
Baker et al[13], 2017	The Renal Association	Recommend treatment when hematocrit > 52% in males and > 49% in females. Recommended first line treatment is ACE-I or ARBs.
McMullin et al[14], 2019	British Society of Hematology	Treat if hematocrit is persistently elevated for > 1 mo with ACE-I or ARB. Therapeutic phlebotomy can be used for persistent symptoms, but there is no evidence of benefit. No evidence for aspirin as an effective treatment.

KDIGO: Kidney Disease Improving Global Outcomes; ACE-I: Angiotensin converting enzyme inhibitors; ARB: Angiotensin receptor blocker; NKF: National Kidney Foundation; KDOQI: Kidney Disease Outcomes Quality Initiative.