Pharmacogenetics of immunosuppressant drugs: A new aspect for individualized therapy

Table 7 Candidate single-nucleotide polymorphisms related to the pharmacodynamics pathways of mycophenolic acid with quality of evidence of existing data and level of recommendation[6]

Drugs	Gene	SNP	MAF	QOE	LOR
Mycophenolic acid	IMPDH2	rs11706052	G = 0.115	A	1
	IMPDG1	rs2278293	A = 0.431	C	4
	IMPDH1	rs2278294	A = 0.323	C	4

Level of recommendation: 1: Highly recommended candidate; 2: Recommended candidate; 3: Potential candidate; 4: Candidate to exclude. SNP: Single-nucleotide polymorphism; MPA: Mycophenolic acid; IMPDH: Inosine monophosphate dehydrogenase; LOR: Level of recommendation; MAF: Minor allele frequency; QOE: Quality of evidence.