Copyright
©2014 Baishideng Publishing Group Inc.
World J Rheumatol. Nov 12, 2014; 4(3): 80-87
Published online Nov 12, 2014. doi: 10.5499/wjr.v4.i3.80
Published online Nov 12, 2014. doi: 10.5499/wjr.v4.i3.80
Figure 1 Hypothetical model of biological link between rheumatoid arthritis and periodontal disease.
ACPA: Anti-citrullinated protein/peptide antibody; CRP: C reative protein; HLA: Human leukocyte antigen; hsp: Heat shock protein; LPS: Lipopolysaccharide, MMPs: Matrix metalloprotienases; NFκB: Nuclear factor kappa β; OPG: Osteoprotegerin; PD: Periodontal disease; PGE2: Prostaglandin E2; RANK: Receptor activator of nuclear factor kappa β; RANKL: Receptor activator of nuclear factor kappa β ligand; RA: Rheumatoid arthritis; RF: Rheumatoid factor; TNF-α: Tumor necrosis factor alpha; ACPA: Anti-citrullinated protein; RF: Rheumatoid factor; P. gingivalis: Porphyromonas gingivalis; IL: Interleukin.
- Citation: Joseph R, Raj MJ, Sundareswaran S, Kaushik PC, Nagrale AV, Jose S, Rajappan S. Does a biological link exist between periodontitis and rheumatoid arthritis? World J Rheumatol 2014; 4(3): 80-87
- URL: https://www.wjgnet.com/2220-3214/full/v4/i3/80.htm
- DOI: https://dx.doi.org/10.5499/wjr.v4.i3.80