Analysis of risk factors leading to anxiety and depression in patients with prostate cancer after castration and the construction of a risk prediction model

Table 1 Comparison of the baseline data between the training group and the validation group

Factors		Training group (n = 84)	Validation group (n = 36)	P value
Age				0.871
	≥ 60 years old	34	14
	< 60 years old	50	22
Education level				0.274
	≥ High school	37	12
	< High school	47	24
Marital status				0.999
	Married	56	24
	Divorced/unmarried	28	12
Employment				0.545
	Employed	19	10
	Retired	65	26
BMI				0.668
	≥ 25 kg/m2	18	9
	< 25 kg/m2	66	27
Smoking history				0.624
	With	62	25
	Without	22	11
History of alcoholism				0.373
	With	13	8
	Without	71	28
Hypertension				0.593
	With	15	5
	Without	69	31
Diabetes mellitus				0.451
	With	18	10
	Without	66	26
Castration scheme				0.778
	Surgery	35	16
	Medication	49	20
Monthly income				0.807
	≥ 4500 RMB	33	15
	< 4500 RMB	51	21
Postoperative VAS score				0.777
	≥ 5 points	19	9
	< 5 points	65	27
Unhealthy emotions
	Bad mood group	35	15
	Emotional stability group	49	21	0.999

BMI: Body mass index; VAS: Visual Analogue Scale.

Table 2 Univariate analysis

Factors		Bad mood group (n = 35)	Emotional stability group (n = 49)	P value
Age				0.645
	≥ 60 years old	15	19
	< 60 years old	20	30
Education level				0.249
	≥ High school	18	19
	< High school	17	30
Marital status				0.034a
	Married	28	28
	Divorced/unmarried	7	21
Employment				0.591
	Employed	7	12
	Retired	28	37
BMI				0.787
	≥ 25 kg/m2	8	10
	< 25 kg/m2	27	39
Smoking history				0.675
	With	25	37
	Without	10	12
History of alcoholism				0.454
	With	4	9
	Without	31	40
Hypertension				0.556
	With	5	10
	Without	30	39
Diabetes mellitus				0.446
	With	6	12
	Without	29	37
Castration scheme				0.003b
	Surgery	21	14
	Medication	14	35
Monthly income				0.010a
	≥ 4500 RMB	8	25
	< 4500 RMB	27	24
Postoperative VAS score				0.007a
	≥ 5 points	13	6
	< 5 points	22	43

^aP < 0.05.

^bP < 0.01.

BMI: Body mass index; VAS: Visual Analogue Scale.

Table 3 Assignment table

Factors	Assignment
Marital status	Married = 1; unmarried/divorced = 0
Castration scheme	Surgery = 1; medication = 0
Monthly income	≥ 4500 RMB = 0; < 4500 RMB = 1
Postoperative VAS score	≥ 5 points = 1; < 5 points = 0
Bad mood	Bad mood = 1; emotional stability = 0

VAS: Visual Analogue Scale.

Table 4 Logistic multivariate regression analysis

Factors	β	Standard error	χ2	P value	OR	95%CI
						Lower bound	Upper bound
Marital status	1.284	0.602	4.554	0.033a	3.611	1.110	11.742
Castration scheme	1.224	0.508	5.805	0.016a	3.401	1.256	9.203
Monthly income	0.614	0.561	1.200	0.273	1.848	0.616	5.547
Postoperative VAS score	1.792	0.646	7.701	0.006b	6.000	1.693	21.27

^aP < 0.05.

^bP < 0.01.

VAS: Visual Analogue Scale.

Table 5 Comparison of the risk scores

Groups	Training group (n = 84)	Groups	Validation group (n = 36)
Bad mood group (n = 35)	2.43 ± 1.00	Bad mood group (n = 15)	2.56 ± 1.14
Emotional stability group (n = 49)	1.30 ± 1.09	Emotional stability group (n = 21)	1.34 ± 1.16
t value	4.813	t value	3.132
P value	< 0.001c	P value	0.004b

^bP < 0.01.

^cP < 0.001.