Role of presynaptic phosphoprotein synapsin II in schizophrenia

Figure 4 Oversimplified diagram of mesolimbic dysregulation in schizophrenia and the mesolimbic system following Antipsychotic drug treatment[94,95]. A: Oversimplified diagram of mesolimbic dysregulation in schizophrenia; B: Oversimplified diagram the mesolimbic system following APD treatment. Difference in neurotransmitter output is indicated through the various line colours (green = glutamatergic, red = GABAergic, blue = dopaminergic). Line thickness is reflective of neurotransmitter activity (thicker lines represent increased activity, dotted lines represent reduced activity). The various impacted brain regions are represented within boxes. CTX: Cortex; NAc: Nucleus accumbens; VTA: Ventral tegmental area; APD: Antipsychotic drug.