Psychiatric aspects of brain tumors: A review

Table 4 Brain tumors and psychotic symptoms[41]

Ref.	Psychiatric symptoms	Tumor location	Tumor type	Remarks
Krayem et al[27], 2014	Psychosis, auditory hallucinations, self-injurious behavior	Right temporal lobe	Astrocytoma	Psychosis developed either from tumor recurrence or right temporal brain tissue loss post-surgery
Kaloshi et al[80], 2013	Visual and auditory hallucinations, spasmodic laughter, minimal spontaneous speech	Cerebellum	Glioneuronal	Partial improvement of symptoms with surgery
Arasappa et al[81], 2013	Lethargy, anhedonia, persecutory delusions, and third person auditory hallucinations	Fourth ventricle	Choroid plexus papilloma	Improvement with surgery
Canuet et al[26], 2011	Schizophrenia-like psychosis	Right parietal lobe	Meningioma	Psychosis developed 6 yr after initial surgery with tumor recurrence. Gradual improvement with antipsychotics
Bunevicius et al[46], 2008	Schizophrenia	Left temporal lobe	Anaplastic oligodendroglioma	Improvement with surgery
Bunevicius et al[46], 2008	Depression, psychosis	Left temporal lobe	Intra-cerebral cyst	Refractory symptoms
Bunevicius et al[46], 2008	Schizophrenia	Left temporal lobe	Glioblastoma multiforme
Parisis et al[82], 2003	Peduncular hallucinosis (complex visual hallucinations), sleep impairment	Cerebellar metastases	Metastases	Mechanism thought to be extrinsic compression of posterior midbrain-pons by mass edema
Rueda-Lara et al[83], 2003	Delusions, hallucinations	Pituitary	Hormone producing adenoma
Maiuri et al[84], 2002	Hallucinations	Posterior thalamus	Glioblastoma multiforme	Partial improvement of symptoms with surgical treatment and antidepressants
Miyazawa et al[85], 2001	Headaches and psychotic symptoms	Pineal	Pineal meningioma	Improvement with surgery
Miyazawa et al[85], 2001	Headaches and psychotic symptoms	Pituitary	Unknown	Improvement with steroid/hormone treatment
Craven[86], 2001	Acute psychotic episode	Pineal	Germinoma
Vardar et al[87], 2000	Psychotic symptoms and cognitive deterioration	Right temporo-parietal	Arachnoid cyst
Mordecai et al[88], 2000	Psychotic and obsessive-compulsive symptoms, left-sided weakness, diabetes insipidus, decline in academic functioning	Bilateral basal ganglia	Germinoma
Werring et al[89], 1999	Visual hallucinations, palinopsia, posterior headache	Occipital	Tuberculoma
Carson et al[90], 1997	Pediatric psychosis - hallucinations, aggression, violence	Third ventricle	Choroid plexus papilloma	Symptoms improved after surgical removal
Ball[91], 1996	Persecutory delusions, auditory and visual hallucinations, fluctuating levels of consciousness followed by grand-mal seizures	Cerebellopontine angle	Meningioma
Filley et al[8], 1995	Psychotic symptoms (perceptual disturbances)	Temporal	Low-grade oligoastrocytoma
Okada et al[92], 1992	Positive and negative psychotic symptoms	Left basal ganglia	Unknown	Positive symptoms resolved after surgical resection, but negative symptoms persisted
Trabert et al[93], 1990	Symptoms of anorexia followed by seizures and psychosis	Temporo-basal	Angioma
Nagaratnam et al[94], 1990	Paranoid delusions	Left frontal lobe	Venous angioma
Ko et al[57], 1989	Paranoid ideation, irritability, short-term memory difficulties	Left parieto-occipital metastatic lesion	Origin in right kidney	No surgical intervention due to advanced stage
Dyck[95], 1985	Auditory hallucinations	Sylvian fissure	Lipoma
Binder[96], 1983	Sudden behavioral changes followed by paranoid delusions; no focal neurologic signs	Right lateral ventricle	Meningioma	Complete resolution of symptoms after surgical intervention
Binder[96], 1983	New-onset rage attacks on background of chronic schizophrenia	Bilateral occipital	Meningioma	Resolution of rage attacks after surgical removal
Dunn et al[97], 1983	Peduncular hallucinations	Midbrain compression	Cystic craniopharyngioma	Prompt resolution after drainage of cyst
Soulairac et al[98], 1979	Peduncular hallucinosis	Right temporal	Astrocytoma
Buchanan et al[99], 1975	Pressured speech, hypomania, persecutory delusions	Lateral ventricle	Meningioma
Blustein et al[73], 1972	Thought disorder, auditory hallucinations	Left parieto-occipital	Porencephalic cyst

Adapted from Trends in Brain Cancer Research. New York: Nova Science Publishers Inc., 2006.