Psychiatric aspects of brain tumors: A review

Table 2 Brain tumors and apathy[41]

Ref.	Psychiatric symptoms	Tumor location	Tumor type	Remarks
Aydin et al[75], 2013	Loss of self-generated behavior, irritability, disinhibition, impulsivity	Midline subfrontal region	Meningioma	Psychiatric and neurologic symptoms with consequent diagnosis of brain tumor
Filley et al[8], 1995	Apathy, social-withdrawal, poor self-care	Bifrontal	Benign meningioma
Filley et al[8], 1995	Apathy, irritability, anomia, right hemiparesis	Left frontal lobe and genu of corpus callosum	Immunoblastic lymphoma
Filley et al[8], 1995	Apathy, amnesia, poor affect	Thalamic and fornical columns	Gonadotropic cell pituitary adenoma
Fulton et al[55], 1992	Loss of interest, poor concentration, withdrawal, lack of communication, neurologic signs	Left frontal lobe involving corpus callosum	Unknown
Tanaghow et al[58], 1989	Depressed mood, social withdrawal, personal neglect, apathy	Anterior corpus callosum	Unknown
Burkle et al[70], 1978	Depression, hypersomnia, anhedonia, low energy, poor concentration, memory lapses	Third ventricle with obstruction of lateral ventricles	Colloid cyst
Avery[74], 1971	Euphoria, drowsiness, and apathy	Tuberculum sellae	Meningioma	Some residual psychiatric disturbance following resection
Avery[74], 1971	Depression, apathy	Right cribriform plate	Meningioma	Post-op manic episode before resolution of symptoms
Avery[74], 1971	Depression, apathy	Right cribriform plate	Meningioma	Improvement after surgery
Avery[74], 1971	Apathy, change in work behavior	Cribriform plate	Meningioma	Improvement after surgery

Adapted from Trends in Brain Cancer Research. New York: Nova Science Publishers Inc., 2006.