Sensation/novelty seeking in psychotic disorders: A review of the literature

Table 7 Sensation/novelty seeking in psychotic patients and control groups

Ref.	n	Trait-instrument	Main findings
Szöke et al[50]	45 schizophrenia inpatients 126 controls	NS, TPQ	No differences in NS between groups
Ritsner et al[51]	90 schizophrenia outpatients 136 controls Drug/alcohol abuse was an exclusion criterion	NS, TPQ	No differences in NS between groups
Calvó de Padilla et al[52]	11 chronic untreated schizophrenia patients 11 first-degree relatives 12 controls	NS, TCI	No differences in NS between groups
Farhady et al[53]	69 schizophrenia inpatients 50 healthy controls	SS, SSS	Lower SS in patients
Hori et al[54]	86 schizophrenia patients 115 healthy controls Substance abuse during the past 6 mo was an exclusion criterion	NS, TCI	Lower NS in patients
Smith et al[55]	35 schizophrenia in- and outpatients 34 non-psychotic siblings 63 controls 56 controls’ siblings Current substance abuse was an exclusion criterion	NS, TCI	No differences in NS between groups. No association of NS with psychopathology dimensions
Gonzalez-Torres et al[56]	61 inpatients with schizophrenia or schizophrenia spectrum disorders 59 first degree relatives 64 healthy controls Substance abuse was an exclusion criterion	NS, TCI	NS scores were not different in patients and controls; patients scored higher on NS than relatives
Ohi et al[57]	99 schizophrenia patients 179 controls Substance-related disorders were an exclusion criterion for patients	NS, TCI	Lower NS in patients
Sim et al[58]	48 patients with schizophrenia or schizoaffective disorder 97 first-degree relatives 106 controls History of substance use was an exclusion criterion	NS, TCI	No differences in NS between groups
Miralles et al[59]	161 schizophrenia inpatients, 214 healthy controls	NS, TCI-R	No differences in NS between groups; in males the number of psychiatric admissions positively correlated with NS
Hori et al[60]	106 schizophrenia outpatients 247 healthy controls Substance use was an exclusion criterion for controls	NS, TCI	NS was found to be significantly lower in symptomatic (n = 72) but not in remitted patients

NS: Novelty seeking; TPQ: Tridimensional personality questionnaire; TCI: Temperament and character inventory; TCI-R: TCI revised; SSS: Sensation Seeking scale; SS: Sensation seeking.