Predictive factors for post-cerebral infarction depression: A retrospective study of 156 patients

Table 2 Stroke-related clinical features, mean ± SD/n (%)

Stroke feature	PSD group (n = 68)	Non-PSD group (n = 88)	P value
NIHSS at admission	8.5 ± 2.6	4.8 ± 1.9	< 0.001
NIHSS at 2 weeks	5.8 ± 2.1	3.2 ± 1.5	< 0.001
Infarct location
Frontal lobe	23 (33.8)	14 (15.9)	0.008
Temporal lobe	12 (17.6)	18 (20.5)	0.656
Parietal lobe	10 (14.7)	15 (17.0)	0.687
Basal ganglia	18 (26.5)	20 (22.7)	0.583
Thalamus	8 (11.8)	7 (8.0)	0.420
Limbic system structures	21 (30.9)	12 (13.6)	0.005
Internal capsule	15 (22.1)	16 (18.2)	0.544
Brainstem	5 (7.4)	8 (9.1)	0.700
Cerebellum	3 (4.4)	5 (5.7)	0.723
Left hemisphere	43 (63.2)	39 (44.3)	0.017
TOAST classification			0.412
Large-artery atherosclerosis	25 (36.8)	28 (31.8)
Cardioembolism	12 (17.6)	14 (15.9)
Small-vessel occlusion	22 (32.4)	35 (39.8)
Other/undetermined	9 (13.2)	11 (12.5)
Onset to admission (hours)	4.8 ± 1.5	3.2 ± 1.0	0.008
SBP at admission (mmHg)	162.3 ± 21.5	151.8 ± 16.2	0.038
Glucose at admission (mmol/L)	7.8 ± 1.6	6.9 ± 1.2	0.025
mRS at 2 weeks	3.2 ± 0.9	1.9 ± 0.8	< 0.001
Barthel Index at 2 weeks	62.5 ± 14.8	81.2 ± 11.3	< 0.001
mRS at 3 months	2.5 ± 1.0	1.3 ± 0.7	< 0.001
Barthel Index at 3 months	72.8 ± 12.5	88.6 ± 9.2	< 0.001

NIHSS: National Institutes of Health Stroke Scale; TOAST: Trial of Org 10172 in Acute Stroke Treatment; SBP: Systolic blood pressure; mRS: Modified Rankin Scale; PSD: Post-stroke depression.