Anxiety-depression comorbidity prevalence in type 2 diabetes mellitus and correlation with insulin resistance

doi:10.5498/wjp.119917

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Sep 19, 2026; 16(9): 119917
Published online Sep 19, 2026. doi: 10.5498/wjp.119917

Table 6 Comparison of insulin resistance incidence

HOMA-IR	T2DM group (n = 40)		T2DM + anxiety group (n = 58)		T2DM + depression group (n = 52)		T2DM + anxiety-depression group (n = 47)		χ²	P value
HOMA-IR	Frequency	Percentage (%)	Frequency	Percentage (%)	Frequency	Percentage (%)	Frequency	Percentage (%)	χ²	P value
HOMA-IR	17	42.5	30	51.7	28	53.8	41	87.2	21.813	< 0.0001
Non-HOMA-IR	23	57.5	28	48.3	24	46.2	6	12.8	21.813	< 0.0001

T2DM: Type 2 diabetes mellitus; HOMA-IR: Homeostasis Model Assessment of Insulin Resistance.

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Citation: Wu CC, Sun WH, Yang QQ, Xue L, Zhao WD. Anxiety-depression comorbidity prevalence in type 2 diabetes mellitus and correlation with insulin resistance. World J Psychiatry 2026; 16(9): 119917
URL: https://www.wjgnet.com/2220-3206/full/v16/i9/119917.htm
DOI: https://dx.doi.org/10.5498/wjp.119917

Wu CC, Sun WH, Yang QQ, Xue L, Zhao WD. Anxiety-depression comorbidity prevalence in type 2 diabetes mellitus and correlation with insulin resistance. World J Psychiatry 2026; 16(9): 119917 [DOI: 10.5498/wjp.119917]

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