Anxiety-depression comorbidity prevalence in type 2 diabetes mellitus and correlation with insulin resistance

doi:10.5498/wjp.119917

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Sep 19, 2026; 16(9): 119917
Published online Sep 19, 2026. doi: 10.5498/wjp.119917

Table 3 Comparison of demographic characteristics

	T2DM group (n = 40)	T2DM + anxiety group (n = 58)	T2DM + depression group (n = 52)	T2DM + anxiety-depression group (n = 47)	F/χ²	P value
Sex					1.411	0.703
Male	18	28	28	20
Female	22	30	24	27
Age (years)	50.70 ± 5.21	51.29 ± 6.85	51.94 ± 6.21	50.19 ± 4.90	0.796	0.497
Body mass index (kg/m²)	22.24 ± 3.59	22.70 ± 3.01	23.10 ± 3.05	23.40 ± 3.16	1.120	0.342
DM course (years)	6.85 ± 3.28	8.81 ± 4.26^a	9.83 ± 4.00^a	9.36 ± 5.11^a	4.112	0.007
Family history of DM					2.264	0.519
Yes	14	21	16	11
No	26	37	36	36
Smoking history					0.094	0.993
Yes	15	23	20	19
No	25	35	32	28
Drinking history					0.183	0.980
Yes	12	19	17	14
No	28	39	35	33
Educational level					1.495	0.960
Junior high school or below	12	18	20	14
Senior high school/technical secondary school	18	26	22	23
University degree or above	10	14	10	10
Marital status					2.690	0.847
Single	7	10	8	5
Married	20	33	31	31
Divorced/widowed	13	15	13	11
Employment status					3.897	0.691
Unemployed	9	13	8	7
Employed	20	29	34	28
Retired	11	16	10	12

^aP < 0.05 vs type 2 diabetes mellitus group.

T2DM: Type 2 diabetes mellitus; DM: Diabetes mellitus.

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Citation: Wu CC, Sun WH, Yang QQ, Xue L, Zhao WD. Anxiety-depression comorbidity prevalence in type 2 diabetes mellitus and correlation with insulin resistance. World J Psychiatry 2026; 16(9): 119917
URL: https://www.wjgnet.com/2220-3206/full/v16/i9/119917.htm
DOI: https://dx.doi.org/10.5498/wjp.119917

Wu CC, Sun WH, Yang QQ, Xue L, Zhao WD. Anxiety-depression comorbidity prevalence in type 2 diabetes mellitus and correlation with insulin resistance. World J Psychiatry 2026; 16(9): 119917 [DOI: 10.5498/wjp.119917]

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