Home-based hospice care alleviates the burden of mental disorders in older patients with advanced cancer

Table 7 Results of multiple linear regression analysis on factors influencing the improvement of mental disorder burden (n = 126)

Independent variables	Model 1 Δ HAMA		Model 2 Δ HAMD		Model 3 Δ PSQI
	β (95%CI)	P value	β (95%CI)	P value	β (95%CI)	P value
Age	-0.105 (-0.420 to 0.210)	0.483	-0.084 (-0.389 to 0.221)	0.601	-0.053 (-0.283 to 0.177)	0.661
Sex	0.085 (-0.224 to 0.394)	0.562	0.117 (-0.185 to 0.419)	0.441	0.041 (-0.187 to 0.269)	0.718
Clinical stage	-0.151 (-0.464 to 0.162)	0.339	-0.250 (-0.564 to -0.010)	0.041	-0.125 (-0.357 to 0.107)	0.262
Living status	-0.179 (-0.492 to 0.134)	0.253	-0.310 (-0.618 to -0.046)	0.021	-0.142 (-0.374 to 0.090)	0.230
Education level	0.187 (-0.121 to 0.495)	0.226	0.351 (0.040 to 0.662)	0.027	0.147 (-0.082 to 0.376)	0.203
Pre-intervention ESAS pain score	-0.283 (-0.594 to -0.029)	0.028	-0.162 (-0.473 to 0.149)	0.311	-0.331 (-0.562 to -0.100)	0.005
Pre-intervention FACT-G social/family well-being score	0.316 (0.006 to 0.626)	0.045	0.267 (-0.043 to 0.577)	0.087	0.176 (-0.051 to 0.403)	0.124
Pre-intervention total PFS-R score	-0.214 (-0.525 to 0.097)	0.185	-0.223 (-0.534 to 0.088)	0.157	-0.287 (-0.518 to -0.056)	0.014
Caregiver training completion	0.374 (0.062 to 0.686)	0.020	0.232 (-0.084 to 0.548)	0.142	0.201 (-0.033 to 0.435)	0.092
Pain control target reached	0.243 (-0.071 to 0.557)	0.128	0.203 (-0.113 to 0.519)	0.206	0.408 (0.176 to 0.640)	0.001
Model statistics	R2 = 0.361, after adjustment R2 = 0.294		R2 = 0.332, after adjustment R2 = 0.264		R2 = 0.398, after adjustment R2 = 0.332
	F = 5.115, P < 0.001		F = 4.475, P < 0.001		F = 6.013, P < 0.001

Δ Hamilton Anxiety Scale/Δ Hamilton Depression Scale/Δ Pittsburgh Sleep Quality Index, pre-intervention score minus post-intervention score. β, standardized regression coefficient, the absolute value indicates the relative influence of the independent variable on the dependent variable. Age, actual value. Sex, male = 1, female = 0. Clinical stage, stage Ⅲ = 0, stage IV = 1. Living status, not-living alone = 0, living alone = 1. Education level, below high school = 0, high school or above = 1. Pre-intervention Edmonton Symptom Assessment System pain score, actual value. Pre-intervention Functional Assessment of Cancer Therapy-General social/family well-being score, actual value. Pre-intervention total Revised Piper Fatigue Scale score, actual value. Caregiver training completion, not all training completed = 0, all training completed = 1. Pain control target reached, not reached = 0, reached = 1. HAMA: Hamilton Anxiety Scale; HAMD: Hamilton Depression Scale; PSQI: Pittsburgh Sleep Quality Index; CI: Confidence interval; ESAS: Edmonton Symptom Assessment System; FACT-G: Functional Assessment of Cancer Therapy-General; PFS-R: Revised Piper Fatigue Scale.