Patient Health Questionnaire-9 and 17-item Hamilton Depression Rating Scale for detecting post-stroke depression in cerebral infarction

Table 3 Comparison of diagnostic efficacy of two scales at different cutoff values

Scale and cutoff value	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	+LR	-LR	Youden Index	Kappa value
HAMD-17 ≥ 7 points	88.39	79.83	67.81	93.47	4.38	0.15	0.682	0.632
PHQ-9 ≥ 5 points	91.07	68.67	58.29	94.12	2.91	0.13	0.597	0.521
PHQ-9 ≥ 7 points	83.04	81.12	67.88	90.87	4.4	0.21	0.642	0.606
PHQ-9 ≥ 10 points	73.21	89.27	76.64	87.39	6.83	0.3	0.625	0.632

HAMD-17: 17-item Hamilton Depression Rating Scale; NPV: Negative predictive value; PHQ-9: Patient Health Questionnaire-9; PPV: Positive predictive value; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio.