Anatomical specificity of post-stroke depression: Subcortical lesions, age-related patterns, and predictors of treatment response

Figure 1 Comparison of treatment efficacy between combined traditional chinese medicine and conventional treatment groups. A: Treatment response rate: The combined traditional Chinese medicine (TCM) group demonstrated significantly higher response rate (89.1%) compared to conventional group (65.6%), χ² = 20.48, ^aP < 0.05; B: Symptom score improvement: Hamilton Anxiety Rating Scale and Hamilton Depression Rating Scale scores showed greater reduction in combined TCM group (12.1 ± 4.2 points and 13.0 ± 4.5 points) vs conventional group (8.2 ± 3.8 points and 8.6 ± 4.0 points), P < 0.01. Error bars represent SD; C: Quality of life and treatment adherence: Combined TCM group exhibited superior SF-36 scores (85.2 ± 12.4 vs 76.8 ± 14.6, P < 0.001) and higher adherence rates (92.2% vs 81.3%, P = 0.012). Data presented as mean ± SD. Combined traditional Chinese medicine group n = 128, Conventional group n = 128. P < 0.001, P < 0.01. HAMA: Hamilton Anxiety Rating Scale; HAMD: Hamilton Depression Rating Scale; TCM: Traditional Chinese medicine.