Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression

doi:10.5498/wjp.116579

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Sep 19, 2026; 16(9): 116579
Published online Sep 19, 2026. doi: 10.5498/wjp.116579

Table 5 Predictors of patients’ curative effects by multivariate modeling

Variable	β	SE	Wald	P value	OR	95%CI
Hyperlipidaemia	1.394	0.602	5.369	0.020	4.030	1.240-13.102
5-HT (ng/mL)	-1.117	0.556	4.039	0.044	0.327	0.110-0.973
DA (ng/mL)	-1.592	0.589	7.315	0.007	0.203	0.064-0.645
Medication regimen	1.331	0.571	5.444	0.020	3.786	1.237-11.583

5-HT: 5-hydroxytryptamine; DA: Dopamine.

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Citation: Zhu ZH, Lin YS, Hong ZQ. Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression. World J Psychiatry 2026; 16(9): 116579
URL: https://www.wjgnet.com/2220-3206/full/v16/i9/116579.htm
DOI: https://dx.doi.org/10.5498/wjp.116579

Zhu ZH, Lin YS, Hong ZQ. Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression. World J Psychiatry 2026; 16(9): 116579 [DOI: 10.5498/wjp.116579]

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