Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression

doi:10.5498/wjp.116579

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Sep 19, 2026; 16(9): 116579
Published online Sep 19, 2026. doi: 10.5498/wjp.116579

Table 3 Safety analysis, n (%)

Indicators	Reference group (n = 56)	Research group (n = 66)	χ²	P value
Nausea	0 (0.00)	2 (3.03)
Celialgia	1 (1.79)	1 (1.52)
Headache	1 (1.79)	0 (0.00)
Drowsiness	3 (5.36)	0 (0.00)
Total	5 (8.93)	3 (4.55)	0.950	0.330

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Citation: Zhu ZH, Lin YS, Hong ZQ. Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression. World J Psychiatry 2026; 16(9): 116579
URL: https://www.wjgnet.com/2220-3206/full/v16/i9/116579.htm
DOI: https://dx.doi.org/10.5498/wjp.116579

Zhu ZH, Lin YS, Hong ZQ. Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression. World J Psychiatry 2026; 16(9): 116579 [DOI: 10.5498/wjp.116579]

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