Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression

doi:10.5498/wjp.116579

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Sep 19, 2026; 16(9): 116579
Published online Sep 19, 2026. doi: 10.5498/wjp.116579

Table 1 General patient data, n (%)

Indicators	Reference group (n = 56)	Research group (n = 66)	χ²/t	P value
Age (years)	59.96 ± 6.89	57.67 ± 8.68
Male	35 (62.50)	40 (60.61)	0.046	0.830
Body mass index (kg/m²)	23.34 ± 2.27	22.74 ± 2.36	1.424	0.157
Stroke course (day)	20.36 ± 5.69	22.36 ± 6.27	1.831	0.070
Infarction site			0.529	0.767
Cortical and subcortical	28 (50.00)	35 (53.03)
Brainstem	15 (26.79)	14 (21.21)
Cerebellum	13 (23.21)	17 (25.76)
Hypertension	15 (26.79)	20 (30.30)	0.183	0.669
Diabetes	23 (41.07)	19 (28.79)	2.025	0.155
Hyperlipidaemia	11 (19.64)	15 (22.73)	0.172	0.679

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Citation: Zhu ZH, Lin YS, Hong ZQ. Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression. World J Psychiatry 2026; 16(9): 116579
URL: https://www.wjgnet.com/2220-3206/full/v16/i9/116579.htm
DOI: https://dx.doi.org/10.5498/wjp.116579

Zhu ZH, Lin YS, Hong ZQ. Efficacy and influencing factors of 3-N-Butylphthalide-trazodone combination in managing post-ischemic stroke depression. World J Psychiatry 2026; 16(9): 116579 [DOI: 10.5498/wjp.116579]

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