Predictive value of serum inflammatory factors combined with p-tau181 for anxiety and depression in Alzheimer’s disease patients

doi:10.5498/wjp.122295

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Aug 19, 2026; 16(8): 122295
Published online Aug 19, 2026. doi: 10.5498/wjp.122295

Table 5 Sensitivity analysis and subgroup analysis

Analysis type	Subgroup	AUC (95%CI)	P value
Primary analysis	Overall (n = 125)	0.892 (0.834-0.950)	-
Stricter criteria	HADS ≥ 10	0.876 (0.812-0.940)	-
Gender-stratified	Male (n = 56)	0.884 (0.802-0.966)	0.724
Gender-stratified	Female (n = 69)	0.898 (0.828-0.968)	-
Cognitive severity	Moderate (MMSE 10-18)	0.912 (0.856-0.968)	0.048
Cognitive severity	Mild (MMSE 19-26)	0.856 (0.772-0.940)	-

AUC: Area under curve; CI: Confidence interval; HADS: Hospital Anxiety and Depression Scale; MMSE: Mini-Mental State Examination.

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Citation: Hu X, Tao J, Jiang YL, Liu K. Predictive value of serum inflammatory factors combined with p-tau181 for anxiety and depression in Alzheimer’s disease patients. World J Psychiatry 2026; 16(8): 122295
URL: https://www.wjgnet.com/2220-3206/full/v16/i8/122295.htm
DOI: https://dx.doi.org/10.5498/wjp.122295

Hu X, Tao J, Jiang YL, Liu K. Predictive value of serum inflammatory factors combined with p-tau181 for anxiety and depression in Alzheimer’s disease patients. World J Psychiatry 2026; 16(8): 122295 [DOI: 10.5498/wjp.122295]

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