Mismatch negativity as a marker for evaluating overall neurocognitive impairment following postconcussion syndrome

doi:10.5498/wjp.121207

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Aug 19, 2026; 16(8): 121207
Published online Aug 19, 2026. doi: 10.5498/wjp.121207

Table 2 The results of mismatch negativity between controls and patients with postconcussion syndrome, mean ± SD

Parameter	Controls (n = 56)	Patients (n = 63)	P value	P_FDR value
Amplitude (μV)
FZ	-3.89 ± 1.79	-2.98 ± 0.99	< 0.001^a	0.0014
F1	-3.97 ± 1.71	-2.94 ± 1.12	< 0.001^a	0.0008
F2	-4.01 ± 1.84	-2.82 ± 1.04	< 0.001^a	0.0002
FCZ	-3.32 ± 1.53	-2.50 ± 0.95	< 0.001^a	0.0014
CZ	-2.42 ± 1.16	-2.15 ± 1.06	0.189	0.2843
PZ	-1.65 ± 0.92	-1.52 ± 0.94	0.459	0.5002
Latency (milliseconds)
FZ	207.17 ± 37.46	216.40 ± 35.06	0.168	0.2841
F1	208.20 ± 35.46	214.95 ± 35.03	0.299	0.3583
F2	206.86 ± 33.45	216.15 ± 35.69	0.146	0.2841
FCZ	208.55 ± 36.56	217.05 ± 33.11	0.186	0.2943
CZ	206.70 ± 39.70	215.75 ± 39.21	0.214	0.2854
PZ	203.46 ± 42.10	208.37 ± 38.97	0.511	0.5112

Data were calculated by Student’s t-test.

^aP < 0.05.

FDR: False discovery rate.

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Citation: Wang JJ, Wu WY, Fang KJ, Yan J, Luo FG, Li HZ. Mismatch negativity as a marker for evaluating overall neurocognitive impairment following postconcussion syndrome. World J Psychiatry 2026; 16(8): 121207
URL: https://www.wjgnet.com/2220-3206/full/v16/i8/121207.htm
DOI: https://dx.doi.org/10.5498/wjp.121207

Wang JJ, Wu WY, Fang KJ, Yan J, Luo FG, Li HZ. Mismatch negativity as a marker for evaluating overall neurocognitive impairment following postconcussion syndrome. World J Psychiatry 2026; 16(8): 121207 [DOI: 10.5498/wjp.121207]

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