Neurobiological mechanisms and clinical implications of scene perception impairment in schizophrenia

Figure 1 A schematic overview of visual pathways and brain networks associated with scene perception in schizophrenia. This figure summarizes the main visual pathways and high-order brain networks associated with scene perception in schizophrenia, illustrating the hierarchical processing of visual information from early processing in the primary visual cortex to the ventral, dorsal and third visual pathways, as well as the interactions between these pathways and large-scale brain systems responsible for network integration and cognitive control. This figure highlights the potential pathological basis of scene perception impairment in schizophrenia: Abnormalities in information flow, effective connectivity and network coordination. LOC: Lateral occipital cortex; dmPFC: Dorso-medial prefrontal cortex; ACC: Anterior cingulate cortex; DMN: Default mode network; MT+: Middle temporal visual area complex; pSTS: Posterior superior temporal sulcus.