Neurobiological mechanisms and clinical implications of scene perception impairment in schizophrenia

Table 3 Structural and white matter magnetic resonance imaging evidence associated with impaired scene perception in schizophrenia

Ref.	Structural MRI domains	Key findings	The structure and meaning	Level of evidence
[8]	Visual cortex retraction/thickness	V1, V2, and the MT+ area increase, the MT+ area selective thinning	This shows that the visual system forms in the center of the perceptual organization and motion analysis area had changed	Directional structure of MRI
[26]	Gray matter in the fusiform gyrus	Fusiform gray matter decreased with facial emotion recognition disorders; reduced spindle volume was associated with diminished N170 responses	Provides a bridge between anatomy and electrophysiology	Structure research
[27]	Rotational phenomena in the schizophrenia spectrum	There was an increase in gyri across the schizophrenia spectrum, consistent with early neurodevelopmental bias	Support the view that the scene perception of vulnerability may partly reflect the change of cortical development	Spectrum structure of MRI
[28]	Local cortical volume abnormality	Extensive cortical volume differences are associated with symptoms and cognition	It is suggested that deficits in scene perception may be limited by a broader load on occipitotemporal and related structures	Clinical form metrology research
[22]	Corpus callosum white matter organization	Structure - function abnormalities involved hemispheres pathways and visual correlation circuits	Means that the complex scene perception required massive consolidation efficiency reduced	Structure and multimodal MRI

MRI: Magnetic resonance imaging; V1: Primary visual cortex; V2: Secondary visual cortex; MT+: Temporal middle visual area complex.