Assessment of nerve growth factor levels and clinical indicators for outcome prediction in first-episode schizophrenia

Figure 2 Receiver operating characteristic curves of serum nerve growth factor-related indicators and their combinations for predicting response to antipsychotic drug treatment. A: Receiver operating characteristic (ROC) curve of sensitivity vs specificity of baseline nerve growth factor (NGF); B: ROC curve of sensitivity vs specificity of NGF at 2 weeks after onset of antipsychotic treatment; C: ROC curve of sensitivity vs specificity of early NGF changes; D: ROC curve of sensitivity vs specificity of combinations of baseline NGF, NGF at 2 weeks after onset of antipsychotic treatment, early NGF changes, and early psychopathological improvement in response to antipsychotic drug treatment. Early nerve growth factor changes: Nerve growth factor at 2 weeks after onset of antipsychotics treatment - baseline nerve growth factor. AUC: Areas under the curve; NGF₀: Baseline nerve growth factor; NGF₁: Nerve growth factor at 2 weeks after onset of antipsychotics treatment.