Effect of sodium valproate on aripiprazole pharmacokinetics and initial dosage optimization in bipolar disorder

doi:10.5498/wjp.v16.i8.120073

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Aug 19, 2026; 16(8): 120073
Published online Aug 19, 2026. doi: 10.5498/wjp.v16.i8.120073

Table 4 Initial dosage recommendation of aripiprazole in patients with bipolar disorder

Patients not receiving sodium valproate sustained-release tablets		Patients receiving sodium valproate sustained-release tablets
Body weight (kg)	Dosage (mg/kg/day)	Body weight (kg)	Dosage (mg/kg/day)
40-120	0.3	40-120	0.4

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Citation: He SM, Zhang CX, Jin YW, Jiang L, Zhang C, Jiang YG, Wang DD. Effect of sodium valproate on aripiprazole pharmacokinetics and initial dosage optimization in bipolar disorder. World J Psychiatry 2026; 16(8): 120073
URL: https://www.wjgnet.com/2220-3206/full/v16/i8/120073.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i8.120073

He SM, Zhang CX, Jin YW, Jiang L, Zhang C, Jiang YG, Wang DD. Effect of sodium valproate on aripiprazole pharmacokinetics and initial dosage optimization in bipolar disorder. World J Psychiatry 2026; 16(8): 120073 [DOI: 10.5498/wjp.v16.i8.120073]

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