Anxiety and depression in Rome IV disorders of gut–brain interaction: Prevalence, clinical impact, and temporal association

Figure 1 Box and whisker plots. A: Comparison of Generalized Anxiety Disorder 7-item scale between overlapping and non-overlapping disorder of gut-brain interactions (DGBI) groups; B: Comparison of the Patient Health Questionnaire 9-item between overlapping and non-overlapping DGBI groups; C: Comparison of Generalized Anxiety Disorder 7-item scale between overlapping and non-overlapping individual DGBIs; D: Comparison of the Patient Health Questionnaire 9-item between overlapping and non-overlapping individual DGBIs. GAD-7: Generalized Anxiety Disorder 7-item; PHQ-9: Patient Health Questionnaire 9-item; DGBI: Disorder of gut-brain interaction; FC: Functional constipation; FD: Functional dyspepsia; FEsD: Functional esophageal disorders; IBS: Irritable bowel syndrome; GD: Gastroduodenal; AD: Anorectal disorder.