Impact of comorbid depression on treatment adherence and long-term urinary function following surgery for benign prostatic hyperplasia

doi:10.5498/wjp.119137

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World Journal of Psychiatry

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2220-3206

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World J Psychiatry. Aug 19, 2026; 16(8): 119137
Published online Aug 19, 2026. doi: 10.5498/wjp.119137

Table 3 Comparison of urinary function parameters between both groups before and after surgery, mean ± SD

Indicator	Group	Pre-operation	6 months post-operation	12 months post-operation	F (group/time/interaction)	P (group/time/interaction)
IPSS score (points)	Comorbidity group	27.35 ± 4.82	15.62 ± 3.45^a^,^b	12.18 ± 2.97^a^,^b	6.681/7.564/5.194	< 0.001/< 0.001/< 0.001
	Non-comorbidity group	26.89 ± 4.67	9.87 ± 2.89^a	6.35 ± 2.12^a	-	-
QOL score (points)	Comorbidity group	5.23 ± 0.89	3.15 ± 0.67^a^,^b	2.56 ± 0.54^a^,^b	5.618/6.024/4.264	< 0.001/< 0.001/< 0.001
	Non-comorbidity group	5.18 ± 0.92	2.01 ± 0.53^a	1.32 ± 0.41^a	-	-
Q_max (mL/second)	Comorbidity group	7.89 ± 2.15	12.35 ± 3.24^a^,^b	15.62 ± 3.87^a^,^b	4.648/5.268/4.915	< 0.001/< 0.001/< 0.001
	Non-comorbidity group	7.67 ± 2.08	16.89 ± 3.56^a	20.35 ± 4.12^a	-	-
PVR (mL)	Comorbidity group	156.23 ± 45.89	89.35 ± 28.67^a^,^b	65.18 ± 22.34^a^,^b	11.264/14.261/10.264	< 0.001/< 0.001/< 0.001
	Non-comorbidity group	152.87 ± 43.65	56.78 ± 21.45^a	38.25 ± 18.67^a	-	-

^aP < 0.05 vs before surgery within the same group.

^bP < 0.05 vs the non-comorbidity group.

IPSS: International Prostate Symptom Score; QOL: Quality of Life; Q_max: Maximum flow rate; PVR: Post-void residual urine volume.

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Citation: Dun WC, Xia Q, Wei ZQ, Li CB. Impact of comorbid depression on treatment adherence and long-term urinary function following surgery for benign prostatic hyperplasia. World J Psychiatry 2026; 16(8): 119137
URL: https://www.wjgnet.com/2220-3206/full/v16/i8/119137.htm
DOI: https://dx.doi.org/10.5498/wjp.119137

Dun WC, Xia Q, Wei ZQ, Li CB. Impact of comorbid depression on treatment adherence and long-term urinary function following surgery for benign prostatic hyperplasia. World J Psychiatry 2026; 16(8): 119137 [DOI: 10.5498/wjp.119137]

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