Risk factors for anxiety and depression in patients with epilepsy and their relationship with quality of life

Table 2 Univariate analysis of anxiety and depression, n (%)/mean ± SD

Factors	Anxiety			Depression			Anxiety/depression
	Negative (n = 65)	Positive (n = 41)	P value	Negative (n = 69)	Positive (n = 37)	P value	Negative (n = 78)	Positive (n = 28)	P value
Age (year)	37.83 ± 2.68	38.54 ± 3.29	0.230	37.84 ± 2.77	38.59 ± 3.21	0.209	37.92 ± 2.86	38.61 ± 3.14	0.293
Disease duration	7.05 ± 1.26	7.61 ± 1.61	0.047	7.07 ± 1.39	7.62 ± 1.44	0.058	7.06 ± 1.33	7.82 ± 1.54	0.015
Gender			0.954			0.123			0.152
Male	25 (38.46)	16 (39.02)		23 (33.33)	18 (48.65)		27 (34.62)	14 (50.00)
Female	40 (61.54)	25 (60.98)		46 (66.67)	19 (51.35)		51 (65.38)	14 (50.00)
Marital status			0.870			0.713			0.486
Married	45 (69.23)	29 (70.73)		49 (71.01)	25 (67.57)		53 (67.95)	21 (75.00)
Unmarried/divorced	20 (30.77)	12 (29.27)		20 (28.99)	12 (32.43)		25 (32.05)	7 (25.00)
Education			0.169			0.019			0.198
High school and above	34 (52.31)	27 (65.85)		34 (49.28)	27 (72.97)		42 (53.85)	19 (67.86)
Junior high school and below	31 (47.69)	14 (34.15)		35 (50.72)	10 (27.03)		36 (46.15)	9 (32.14)
Employment status			0.038			0.025			0.018
Employed	49 (75.38)	23 (56.10)		52 (75.36)	20 (54.05)		58 (74.36)	14 (50.00)
Unemployed	16 (24.62)	18 (43.90)		17 (24.64)	17 (45.95)		20 (25.64)	14 (50.00)
Number of antiepileptic drugs			0.249			0.017			0.020
≤ 2	36 (55.38)	18 (43.90)		41 (59.42)	13 (35.14)		45 (57.69)	9 (32.14)
> 2	29 (44.62)	23 (56.10)		28 (40.58)	24 (64.86)		33 (42.31)	19 (67.86)
Seizure type			0.900			0.245			0.367
Focal seizures	23 (35.38)	15 (36.59)		22 (31.88)	16 (43.24)		26 (33.33)	12 (42.86)
Generalised seizures	42 (64.62)	26 (63.41)		47 (68.12)	21 (56.76)		52 (66.67)	16 (57.14)
Monthly seizure frequency			0.019			0.007			0.003
≤ 2	42 (64.62)	17 (41.46)		45 (65.22)	14 (37.84)		50 (64.10)	9 (32.14)
> 2	23 (35.38)	24 (58.54)		24 (34.78)	23 (62.16)		28 (35.90)	19 (67.86)