Fluoxetine plus psychological intervention for chemotherapy-managed colon cancer patients: Impact on mood and influencing factors

doi:10.5498/wjp.117931

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Aug 19, 2026; 16(8): 117931
Published online Aug 19, 2026. doi: 10.5498/wjp.117931

Table 3 Clinical safety evaluation, n (%)

Safety	Control group (n = 66)	Observation group (n = 79)	χ² value	P value
Mucositis	2 (3.03)	2 (2.53)	0.033	0.855
Diarrhea	6 (9.09)	4 (5.06)	0.908	0.341
Alopecia	8 (12.12)	7 (8.86)	0.412	0.521
Anorexia	13 (19.70)	10 (12.66)	1.335	0.248
Nausea	2 (3.03)	4 (5.06)	0.375	0.541
Insomnia	1 (1.52)	3 (3.80)	0.698	0.403
Sexual dysfunction	0 (0.00)	0 (0.00)	-	-
Agitation	0 (0.00)	0 (0.00)	-	-

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Citation: Zhu XX, Zhao S, Xu Q, Tang R, Xu LX, Zhou YJ, Zhang DY. Fluoxetine plus psychological intervention for chemotherapy-managed colon cancer patients: Impact on mood and influencing factors. World J Psychiatry 2026; 16(8): 117931
URL: https://www.wjgnet.com/2220-3206/full/v16/i8/117931.htm
DOI: https://dx.doi.org/10.5498/wjp.117931

Zhu XX, Zhao S, Xu Q, Tang R, Xu LX, Zhou YJ, Zhang DY. Fluoxetine plus psychological intervention for chemotherapy-managed colon cancer patients: Impact on mood and influencing factors. World J Psychiatry 2026; 16(8): 117931 [DOI: 10.5498/wjp.117931]

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