Fluoxetine plus psychological intervention for chemotherapy-managed colon cancer patients: Impact on mood and influencing factors

doi:10.5498/wjp.117931

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Aug 19, 2026; 16(8): 117931
Published online Aug 19, 2026. doi: 10.5498/wjp.117931

Table 1 General data analysis, n (%)

Data	n	Control group (n = 66)	Observation group (n = 79)	t/Z/χ² value	P value
Sex				0.570	0.450
Male	84	36 (54.55)	48 (60.76)
Female	61	30 (45.45)	31 (39.24)
Age (years)	145	59.62 ± 13.00	59.19 ± 9.10	0.233	0.816
Disease duration (months)	145	7.00 (5.75, 8.00)	7.00 (6.00, 9.00)	0.316	0.752
Tumor diameter (cm)	145	4.06 ± 1.42	4.26 ± 1.73	0.751	0.454
Lesion location				0.469	0.494
Left hemicolon	68	33 (50.00)	35 (44.30)
Right hemicolon	77	33 (50.00)	44 (55.70)
TNM staging				1.293	0.255
II	50	26 (39.39)	24 (30.38)
III	95	40 (60.61)	55 (69.62)
Chemotherapy regimen				0.425	0.514
mFOLFOX6	77	37 (56.06)	40 (50.63)
FOLFIRI	68	29 (43.94)	39 (49.37)
Educational level				0.055	0.815
Below senior high school	60	28 (42.42)	32 (40.51)
Senior high school or above	85	38 (57.58)	47 (59.49)

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Citation: Zhu XX, Zhao S, Xu Q, Tang R, Xu LX, Zhou YJ, Zhang DY. Fluoxetine plus psychological intervention for chemotherapy-managed colon cancer patients: Impact on mood and influencing factors. World J Psychiatry 2026; 16(8): 117931
URL: https://www.wjgnet.com/2220-3206/full/v16/i8/117931.htm
DOI: https://dx.doi.org/10.5498/wjp.117931

Zhu XX, Zhao S, Xu Q, Tang R, Xu LX, Zhou YJ, Zhang DY. Fluoxetine plus psychological intervention for chemotherapy-managed colon cancer patients: Impact on mood and influencing factors. World J Psychiatry 2026; 16(8): 117931 [DOI: 10.5498/wjp.117931]

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