Incidence, risk factors, and correlation with organ involvement of psychological disorders in patients with Sjögren’s syndrome

Table 2 Incidence and related characteristics analysis of psychological disorders in patients with Sjögren’s syndrome, n (%)

Variable	Psychological disorder group (n = 156)	Non-psychological disorder group (n = 130)	Statistical value	P value
Distribution of psychological disorder types
Pure depression	58 (20.3)
Pure anxiety	38 (13.3)
Depression-anxiety comorbidity	60 (21.0)
Psychological assessment scale scores (mean ± SD)
HAMD score (points)	14.7 ± 6.2	3.2 ± 2.1	t = 22.15	< 0.001
HAMA score (points)	12.3 ± 5.8	2.8 ± 1.9	t = 19.84	< 0.001
Severity of psychological disorders
Mild	89 (31.1)
Moderate	46 (16.1)
Severe	21 (7.3)
Severity of depression
Mild depression	69 (58.5)
Moderate depression	35 (29.7)
Severe depression	14 (11.9)
Severity of anxiety
Mild anxiety	54 (55.1)
Moderate anxiety	32 (32.7)
Severe anxiety	12 (12.2)
Demographic characteristics
Female	144 (92.3)	110 (84.6)	χ² = 4.15	0.042
Age ≥ 50 years	107 (68.6)	64 (49.2)	χ² = 11.07	0.001
Age (years, mean ± SD)	52.8 ± 12.4	48.6 ± 11.7	t = 3.84	< 0.001
Disease characteristics
Disease duration ≥ 5 years	102 (65.4)	62 (47.7)	χ² = 9.18	0.002
Disease duration (years, mean ± SD)	6.8 ± 4.2	4.9 ± 3.1	t = 4.52	< 0.001

HAMD: Hamilton Depression Rating Scale; HAMA: Hamilton Anxiety Rating Scale.