Divergent lymphocyte associations with depression severity and case status in first-episode, drug-naive adolescents: A multicenter study

Table 2 Social demographic and clinical immunological characteristics of each group, n (%)/mean ± SD/median (interquartile rage)

Variables	Depression		Total	t/χ2/Z	P value
	No	Yes
Total	41 (50)	41 (50)	82 (100)
Age	15.29 ± 2.33	15.00 ± 2.06	15.15 ± 2.19	0.25	0.619
Sex				1.92	0.165
Male	18 (62.07)	11 (37.93)	29 (41.54)
Female	23 (43.40)	30 (56.60)	53 (58.46)
WBC (× 109/L)	7.47 (1.60)	6.55 (1.45)	7.01 (1.59)	2.73	0.007
Neutrophils (× 109/L)	4.57 (3.44-5.32)	3.32 (2.46-4.51)	3.80 (2.76-4.84)	2.79	0.005
Lymphocytes (× 109/L)	2.96 (2.25-3.92)	2.37 (1.99-2.89)	2.64 (2.14-3.05)	2.97	0.002
Monocytes (× 109/L)	0.45 (0.13)	0.44 (0.11)	0.45 (0.12)	0.46	0.647
LNR	0.68 (0.49-0.86)	0.78 (0.53-1.00)	0.71 (0.51-0.94)	0.57	0.568
NMR	10.12 (7.91-11.89)	7.82 (6.18-9.45)	8.50 (6.74-10.66)	2.50	0.012
LMR	6.41 (5.49-8.24)	5.66 (4.42-6.97)	6.10 (4.71-7.48)	2.01	0.044

WBC: White blood cell; LNR: Lymphocyte-to-neutrophil ratio; NMR: Neutrophil-to-monocyte ratio; LMR: Lymphocyte-to-monocyte ratio.