Serum adiponectin and cognitive function in Alzheimer’s disease with comorbid depression

Table 5 Multiple linear regression analysis in the observation group

Independent variable	B	SE	β	t	P value
Constant	17.328	3.655	-	4.741	< 0.001
FPG	-0.237	0.158	-0.092	-1.502	0.136
TC	-0.638	0.361	-0.121	-1.767	0.080
TG	-1.116	1.161	-0.061	-0.962	0.338
HDL-C	1.043	0.989	0.057	1.055	0.294
LDL-C	-0.149	0.350	-0.024	-0.426	0.671
hs-CRP	-0.457	0.337	-0.088	-1.353	0.179
Serum APN	1.104	0.138	0.601	8.009	< 0.001

This table shows the results of multiple linear regression analysis to assess the independent association between serum adiponectin (APN) levels and Montreal Cognitive Assessment (MoCA) score after adjusting for metabolic and inflammatory factors (fasting plasma glycemia, total cholesterin, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, high-sensitivity c-reactive protein). Serum APN remained a significant independent predictor of MoCA score (β = 0.601, P < 0.001), suggesting its potential role in cognitive function independent of these confounders. APN: Adiponectin; FPG: Fasting plasma glycemia; TC: Total cholesterin; TG: Triglycerides; HDL-C: High-density lipoprotein cholesterol; LDL-C: Low-density lipoprotein cholesterol; hs-CRP: High-sensitivity C-reactive protein.