Copyright: ©Author(s) 2026.
World J Psychiatry. Jul 19, 2026; 16(7): 117824
Published online Jul 19, 2026. doi: 10.5498/wjp.117824
Published online Jul 19, 2026. doi: 10.5498/wjp.117824
Table 3 Comparison of Hamilton depression total and index scores in male and female schizophrenia patients with and without tardive dyskinesia
| Male | Female | |||||||
| TD | Non-TD | Z | P value | TD | Non-TD | Z | P value | |
| Anxiety somatization | 2 (0, 3) | 2 (0, 3) | 1.091 | 0.275 | 2 (2, 4) | 2 (1, 3.75) | 1.803 | 0.071 |
| Weight loss | 0 (0, 0) | 0 (0, 0) | 0.91 | 0.927 | 0 (0, 0) | 0 (0, 0) | 0.718 | 0.473 |
| Cognitive disturbances | 1 (0, 2) | 0 (0, 2) | 1.729 | 0.084 | 2 (0, 3) | 1 (0, 3.75) | 1.544 | 0.123 |
| Diurnal variation | 0 (0, 0) | 0 (0, 0) | 3.259 | 0.001 | 0 (0, 1) | 0 (0, 0) | 4.906 | < 0.001 |
| Psychomotor retardation | 1 (0, 3) | 1 (0, 3) | 0.732 | 0.464 | 3 (1, 4) | 1 (0, 3) | 2.496 | 0.013 |
| Insomnia | 0 (0, 1) | 0 (0, 2) | 0.420 | 0.674 | 0 (0, 1) | 0 (0, 1) | 0.971 | 0.332 |
| Hopelessness | 0 (0, 1.5) | 0 (0, 1.75) | 1.340 | 0.180 | 1 (0, 2.5) | 0.5 (0, 2) | 1.253 | 0.210 |
| HAMD total score | 6 (3, 11) | 6 (2, 10) | 0.670 | 0.503 | 10 (5, 14) | 7 (2, 13) | 2.034 | 0.042 |
- Citation: Xiao SR, Yin QY, Zhu JM, Liu Y, Tan WZ, Wang T, Zhang XY. Tardive dyskinesia-depression association in Chinese patients with chronic schizophrenia: The mediating role of insomnia and gender differences. World J Psychiatry 2026; 16(7): 117824
- URL: https://www.wjgnet.com/2220-3206/full/v16/i7/117824.htm
- DOI: https://dx.doi.org/10.5498/wjp.117824