Effects of paroxetine on aripiprazole and individualized administration in depressed patients based on model-informed precision dosing

Table 1 Demographic data of depressed patients with aripiprazole (n = 87), mean ± SD

Characteristic	mean ± SD	Median (range)
Gender (men/women)	30/57	-
Age (years)	25.81 ± 14.18	20.06 (12.73-72.21)
Weight (kg)	65.49 ± 16.81	60.00 (40.00-108.00)
Albumin (g/L)	42.30 ± 3.19	42.20 (35.30-50.00)
Globulin (g/L)	26.21 ± 3.52	25.90 (19.10-40.60)
Alanine transaminase (IU/L)	24.28 ± 16.27	20.00 (6.00-101.00)
Aspartate transaminase (IU/L)	20.83 ± 9.57	18.00 (10.00-70.00)
Creatinine (μmol/L)	59.18 ± 13.76	56.00 (38.00-93.00)
Urea (mmol/L)	4.26 ± 1.17	4.12 (2.24-7.66)
Total protein (g/L)	68.51 ± 4.67	68.00 (59.90-83.60)
Triglyceride (mmol/L)	1.59 ± 1.02	1.19 (0.28-4.47)
Direct bilirubin (μmol/L)	2.73 ± 1.13	2.60 (0.40-6.00)
Total bilibrubin (μmol/L)	8.58 ± 3.81	8.00 (2.30-26.70)
Hematocrit (%)	40.04 ± 4.41	39.80 (31.10-49.10)
Hemoglobin (g/L)	133.16 ± 16.78	130.00 (99.00-169.00)
Mean corpuscular hemoglobin (pg)	29.84 ± 2.06	30.00 (21.50-34.10)
Mean corpuscular hemoglobin concentration (g/L)	332.10 ± 11.21	333.00 (302.00-359.00)