Effect of apple phenols on anxiety/depression in a rat model of acute exacerbation of chronic obstructive pulmonary disease

Figure 6 Comparison the levels of depression and anxiety in different groups of rats. A: Sucrose preference rate; B: The total distance; C: Number of entries to the central area; D: Duration of stay in the central area. ^aP < 0.01 vs control group, ^cP < 0.01 vs model group, ^dP < 0.05 vs low-dose apple polyphenols (AP), ^eP < 0.05 vs middle-dose AP,^fP < 0.05 vs high-dose AP. AP-L: Low-dose apple polyphenols; AP-M: Middle-dose apple polyphenols; AP-H: High-dose apple polyphenols; AP-H + mcc950: High-dose apple polyphenols + NOD-like receptor protein 3 inhibitor.