Effect of esketamine-assisted regional block on post-traumatic stress disorder after radical lung cancer surgery: A retrospective clinical study

Table 4 Comparison of serum cortisol, interleukin-6 levels, and pain scores, mean ± SD

Parameters	Control group (n = 106)	Esketamine group (n = 112)	P value
Serum cortisol (nmol/L)
24 hours postoperative	458.3 ± 92.6	326.4 ± 68.2	< 0.001
Serum IL-6 (pg/mL)
24 hours postoperative	68.4 ± 18.2	42.8 ± 12.6	< 0.001
VAS pain scores
6 hours postoperative	5.2 ± 1.4	3.8 ± 1.2	< 0.001
24 hours postoperative	4.6 ± 1.2	3.2 ± 1.0	< 0.001
48 hours postoperative	3.8 ± 1.0	2.6 ± 0.8	< 0.001
72 hours postoperative	3.2 ± 0.8	2.2 ± 0.6	< 0.001

P values were calculated using independent samples t-test. IL: Interleukin; VAS: Visual Analog Scale.