Effect of esketamine-assisted regional block on post-traumatic stress disorder after radical lung cancer surgery: A retrospective clinical study

doi:10.5498/wjp.v16.i6.119817

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Jun 19, 2026; 16(6): 119817
Published online Jun 19, 2026. doi: 10.5498/wjp.v16.i6.119817

Table 1 Baseline characteristics of patients, n (%)/mean ± SD

Characteristics	Control group (n = 106)	Esketamine group (n = 112)
Age (years)	58.8 ± 9.6	58.1 ± 8.9
Male	67 (63.2)	67 (59.8)
BMI (kg/m²)	23.4 ± 3.2	23.8 ± 3.4
ASA classification II/III	82/24	88/24
Tumor stage I/II/III	46/38/22	52/40/20
Surgical approach (VATS/open)	74/32	80/32
Preoperative cortisol (nmol/L)	284.6 ± 52.4	278.2 ± 48.6
Preoperative IL-6 (pg/mL)	12.4 ± 3.8	11.8 ± 3.6

No significant differences were observed between groups (all P > 0.05). BMI: Body mass index; ASA: American Society of Anesthesiologists; VATS: Video-assisted thoracoscopic surgery; IL-6: Interleukin-6.

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Citation: Chen YL, Feng TC, Zhang XM, Liu N, Yuan HM, Bian R, Yao J, Xing Z. Effect of esketamine-assisted regional block on post-traumatic stress disorder after radical lung cancer surgery: A retrospective clinical study. World J Psychiatry 2026; 16(6): 119817
URL: https://www.wjgnet.com/2220-3206/full/v16/i6/119817.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i6.119817

Chen YL, Feng TC, Zhang XM, Liu N, Yuan HM, Bian R, Yao J, Xing Z. Effect of esketamine-assisted regional block on post-traumatic stress disorder after radical lung cancer surgery: A retrospective clinical study. World J Psychiatry 2026; 16(6): 119817 [DOI: 10.5498/wjp.v16.i6.119817]

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