Preoperative anxiety and depression predict two-year outcomes after total hip or knee arthroplasty

Table 6 Multivariate logistic regression analysis of the impact of preoperative anxiety and depression on 2-year postoperative outcomes¹

Dependent variable	Independent variable	β	SE	Wald χ2	P value	OR	95%CI
Poor joint function at 2 years postoperatively	Preoperative anxiety and depression (yes vs no)	1.346	0.353	14.532	< 0.001	3.84	1.92-7.68
(n = 48/184, 26.1%)	Age (≥ 65 years vs < 65 years)2	0.682	0.328	4.325	0.038	1.98	1.04-3.77
	Gender (female vs male)	0.245	0.315	0.605	0.437	1.28	0.69-2.37
	BMI (≥ 28 kg/m2 vs < 28 kg/m2)3	0.534	0.336	2.526	0.112	1.71	0.88-3.31
	Surgery type (TKA vs THA)	0.412	0.308	1.786	0.181	1.51	0.83-2.76
	Hypertension (yes vs no)	0.328	0.321	1.043	0.307	1.39	0.74-2.61
	Diabetes (yes vs no)	0.587	0.342	2.947	0.086	1.8	0.92-3.52
Complication occurrence at 2 years postoperatively	Preoperative anxiety and depression (yes vs no)	0.982	0.374	6.895	0.009	2.67	1.28-5.57
(n = 40/184, 21.7%)	Age (≥ 65 years vs < 65 years)2	0.738	0.352	4.397	0.036	2.09	1.05-4.16
	Gender (female vs male)	0.186	0.342	0.296	0.586	1.2	0.61-2.37
	BMI (≥ 28 kg/m2 vs < 28 kg/m2)3	0.624	0.361	2.989	0.084	1.87	0.92-3.79
	Surgery type (TKA vs THA)	0.298	0.335	0.791	0.374	1.35	0.70-2.60
	Hypertension (yes vs no)	0.453	0.347	1.704	0.192	1.57	0.80-3.10
	Diabetes (yes vs no)	0.712	0.368	3.743	0.053	2.04	0.99-4.19

¹Numbers in parentheses represent the number of outcome events/total number of cases (incidence %).

²Age classification threshold of 65 years based on the demographic definition of the elderly.

³Body mass index classification threshold of 28 kg/m² based on Chinese adult obesity diagnostic standard (WS/T 428-2013); Hosmer-Lemeshow goodness-of-fit test P-values for both models are > 0.05, indicating good model fit.

OR: Odds ratio; CI: Confidence interval; THA: Total hip arthroplasty; TKA: Total knee arthroplasty; BMI: Body mass index.