Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction

Table 7 Multiple linear regression analysis of factors influencing Hamilton Depression Rating Scale-17 items scores at 6 months

Variable	Regression coefficient (β)	SE	Standardized coefficient	t value	P value	95%CI
Age	0.124	0.028	0.234	4.429	< 0.001	0.069-0.179
NIHSS score	0.346	0.075	0.287	4.613	< 0.001	0.198-0.494
hs-CRP	0.187	0.068	0.142	2.750	0.006	0.053-0.321
MMSE score	-0.308	0.098	-0.176	-3.143	0.002	-0.501 to -0.115
Infarct size (large)	1.426	0.634	0.108	2.249	0.025	0.179-2.673
Onset to admission time	0.048	0.023	0.087	2.087	0.038	0.003-0.093
Baseline depression score	0.285	0.098	0.156	2.908	0.004	0.092-0.478
Social support score	-0.142	0.067	-0.089	-2.119	0.035	-0.274 to 0.010

R² = 0.428, adjusted R² = 0.408, F = 19.267, P < 0.001, model passed collinearity diagnosis, all variance inflation factor values < 2.5. CI: Confidence interval; NIHSS: National Institutes of Health Stroke Scale; hs-CRP: High-sensitivity C-reactive protein; MMSE: Mini-Mental State Examination.