Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction

doi:10.5498/wjp.v16.i6.115917

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Jun 19, 2026; 16(6): 115917
Published online Jun 19, 2026. doi: 10.5498/wjp.v16.i6.115917

Table 5 Changes in Mini-Mental State Examination scores over time among different age groups, mean ± SD

Time point	Young group (n = 68)	Middle-aged group (n = 124)	Elderly group (n = 108)	F value	P value
At discharge	26.8 ± 2.4	25.1 ± 3.2	22.6 ± 4.1	32.847	< 0.001
1-month post-discharge	25.9 ± 2.7	24.2 ± 3.5	21.3 ± 4.4	28.156	< 0.001
3-month post-discharge	27.2 ± 2.3	25.8 ± 3.1	22.8 ± 4.0	35.742	< 0.001
6-month post-discharge	27.6 ± 2.1	26.3 ± 2.9	23.5 ± 3.8	38.924	< 0.001

Repeated measures analysis of variance results: Time effect F = 18.432, P < 0.001; between-group effect F = 45.628, P < 0.001; time × group interaction effect F = 5.247, P = 0.002.

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Citation: Li JJ, Chen ZJ, Nian WH, Liang YL, Su WJ. Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction. World J Psychiatry 2026; 16(6): 115917
URL: https://www.wjgnet.com/2220-3206/full/v16/i6/115917.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i6.115917

Li JJ, Chen ZJ, Nian WH, Liang YL, Su WJ. Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction. World J Psychiatry 2026; 16(6): 115917 [DOI: 10.5498/wjp.v16.i6.115917]

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