Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction

Table 3 Comparison of laboratory parameters among different age groups, mean ± SD

Item	Young group (n = 68)	Middle-aged group (n = 124)	Elderly group (n = 108)	F value	P value
Blood routine
White blood cells (× 109/L)	8.2 ± 2.4	8.8 ± 2.9	9.1 ± 3.2	2.847	0.059
Neutrophil percentage (%)	69.2 ± 8.5	71.8 ± 9.3	73.5 ± 10.1	6.124	0.002
Hemoglobin (g/L)	132 ± 18	128 ± 19	124 ± 21	4.258	0.015
Platelets (× 109/L)	248 ± 67	265 ± 82	278 ± 94	3.156	0.044
Biochemical indicators
Blood glucose (mmol/L)	6.5 ± 1.8	7.2 ± 2.4	8.1 ± 2.9	11.567	< 0.001
Creatinine (μmol/L)	76 ± 16	84 ± 21	92 ± 28	12.483	< 0.001
Blood urea nitrogen (mmol/L)	5.1 ± 1.6	5.8 ± 2.1	6.8 ± 2.5	15.234	< 0.001
Alanine aminotransferase (U/L)	28 ± 12	32 ± 16	35 ± 19	3.924	0.021
Aspartate aminotransferase (U/L)	31 ± 14	36 ± 18	42 ± 23	6.785	0.001
Total cholesterol (mmol/L)	4.8 ± 1.1	4.6 ± 1.0	4.4 ± 1.2	3.154	0.044
Triglycerides (mmol/L)	1.9 ± 1.0	2.2 ± 1.3	2.0 ± 1.1	2.687	0.070
Electrolytes
Serum sodium (mmol/L)	139.2 ± 2.8	139.1 ± 3.2	138.8 ± 3.8	0.326	0.722
Serum potassium (mmol/L)	4.1 ± 0.4	4.0 ± 0.5	4.0 ± 0.6	0.847	0.430
Serum chloride (mmol/L)	102.5 ± 3.8	101.9 ± 4.1	100.7 ± 4.9	4.126	0.017
Serum calcium (mmol/L)	2.38 ± 0.15	2.35 ± 0.18	2.29 ± 0.21	5.687	0.004
Serum phosphorus (mmol/L)	1.18 ± 0.24	1.22 ± 0.28	1.28 ± 0.32	2.845	0.060
Cardiac enzymes
Creatine kinase (U/L)	142 ± 52	156 ± 68	168 ± 75	3.847	0.022
Creatine kinase-MB (U/L)	16 ± 7	19 ± 9	22 ± 11	4.124	0.017
Lactate dehydrogenase (U/L)	198 ± 45	218 ± 58	235 ± 67	8.562	< 0.001
Other indicators
Prothrombin time (second)	12.8 ± 1.4	13.2 ± 1.8	14.1 ± 2.3	9.234	< 0.001
Activated partial thromboplastin time (second)	31.5 ± 4.2	33.1 ± 5.6	36.8 ± 7.1	15.647	< 0.001
Troponin I (ng/mL)	0.03 ± 0.04	0.06 ± 0.09	0.09 ± 0.15	6.147	0.002
HbA1c (%)	6.2 ± 1.1	6.8 ± 1.4	7.5 ± 1.8	15.832	< 0.001
hs-CRP (mg/L)	3.2 ± 2.1	5.8 ± 3.4	8.9 ± 4.7	42.578	< 0.001
Homocysteine (μmol/L)	12.4 ± 3.8	15.7 ± 4.9	19.3 ± 6.2	36.124	< 0.001
BNP (pg/mL)	156 ± 89	234 ± 156	387 ± 234	28.964	< 0.001

BNP: B-type natriuretic peptide; HbA1c: Glycated hemoglobin; hs-CRP: High-sensitivity C-reactive protein.