Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction

doi:10.5498/wjp.v16.i6.115917

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World Journal of Psychiatry

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2220-3206

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World J Psychiatry. Jun 19, 2026; 16(6): 115917
Published online Jun 19, 2026. doi: 10.5498/wjp.v16.i6.115917

Table 1 Comparison of baseline characteristics among different age groups, mean ± SD/n (%)

Item	Young group (n = 68)	Middle-aged group (n = 124)	Elderly group (n = 108)	χ²/F value	P value
Gender				4.126	0.127
Male	45 (66.2)	89 (71.8)	63 (58.3)
Female	23 (33.8)	35 (28.2)	45 (41.7)
BMI (kg/m²)	24.6 ± 3.2	25.3 ± 3.8	23.9 ± 3.5	4.127	0.017
Education level				15.672	0.004
Junior high school or below	18 (26.5)	52 (41.9)	67 (62.0)
High school	28 (41.2)	46 (37.1)	31 (28.7)
College or above	22 (32.3)	26 (21.0)	10 (9.3)
Marital status				12.864	0.002
Married	52 (76.5)	108 (87.1)	83 (76.9)
Single/divorced/widowed	16 (23.5)	16 (12.9)	25 (23.1)
Medical history
Hypertension	28 (41.2)	78 (62.9)	89 (82.4)	24.571	< 0.001
Diabetes	12 (17.6)	35 (28.2)	48 (44.4)	12.398	0.002
Coronary heart disease	5 (7.4)	23 (18.5)	34 (31.5)	13.962	0.001
NIHSS score	8.2 ± 4.6	10.5 ± 5.3	12.1 ± 5.8	19.854	< 0.001
mRS score	2.1 ± 1.2	2.8 ± 1.4	3.2 ± 1.5	21.472	< 0.001
Infarct location				2.185	0.335
Anterior circulation	48 (70.6)	92 (74.2)	84 (77.8)
Posterior circulation	20 (29.4)	32 (25.8)	24 (22.2)

BMI: Body mass index; NIHSS: National Institutes of Health Stroke Scale; mRS: Modified Rankin Scale.

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Citation: Li JJ, Chen ZJ, Nian WH, Liang YL, Su WJ. Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction. World J Psychiatry 2026; 16(6): 115917
URL: https://www.wjgnet.com/2220-3206/full/v16/i6/115917.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i6.115917

Li JJ, Chen ZJ, Nian WH, Liang YL, Su WJ. Age-stratified analysis of depression onset patterns and treatment response differences following cerebral infarction. World J Psychiatry 2026; 16(6): 115917 [DOI: 10.5498/wjp.v16.i6.115917]

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