Association between vascular risk factor clustering and post-stroke depression

Table 3 Sensitivity analysis and subgroup analysis

Analysis type	Subgroup	High-risk group (≥ 3 factors)	Low-risk group (≤ 2 factors)	Statistical results
Primary sensitivity analysis
HAMD-17 ≥ 14 criteria	Overall (n = 110)	58.6 (34/58)	30.8 (16/52)	χ2 = 8.64, P = 0.003
Gender-stratified analysis
HAMD-17 ≥ 14 criteria	Male patients (n = 65)	47.1 (16/34)	19.4 (6/31)	P = 0.015
HAMD-17 ≥ 14 criteria	Female patients (n = 45)	54.2 (13/24)	28.6 (6/21)	P = 0.065
Age-stratified analysis
Odds ratio	≥ 65 years	OR = 4.56	Reference	95%CI: 1.68-12.38
Odds ratio	< 65 years	OR = 2.12	Reference	95%CI: 0.72-6.25
Alternative grouping scheme
≤ 1 risk factors vs ≥ 2 risk factors	Overall	≥ 2 factors	≤ 1 factor	OR = 3.12 (95%CI: 1.42-6.87), P = 0.005

HAMD-17: Hamilton Depression Rating Scale-17; OR: Odds ratio; CI: Confidence interval.