Exploring the antidepressant mechanisms of Guipi pill: A focus on gut-brain axis and immunity modulation

doi:10.5498/wjp.v16.i6.114553

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. Jun 19, 2026; 16(6): 114553
Published online Jun 19, 2026. doi: 10.5498/wjp.v16.i6.114553

Table 1 The detailed information of the platform

Series number	Platform	Number of patients	Number of healthy controls	Sample type
GSE10616	GPL5760 (Affymetrix GeneChip Human Genome U133 Plus 2.0 Array)	42	16	Ileum and colon
GSE20881	GPL1708 (Agilent-012391 Whole Human Genome Oligo Microarray G4112A)	99	73	Ileum and colon
GSE179285	GPL6480 (Agilent-014850 Whole Human Genome Microarray 4x44K G4112F)	223	31	Ileum and colon
GSE19738	GPL6848 (Agilent-012391 Whole Human Genome Oligo Microarray G4112A)	34	33	Whole blood
GSE52790	GPL17976 (hGlue_3_0_v1 Affymetrix Human hGlue_3_0_v1 Array)	12	10	Whole blood
GSE98793	GPL570 (HG-U133_Plus_2 Affymetrix Human Genome U133 Plus 2.0 Array)	64	128	Whole blood

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Citation: Zhong J, Chen W, Li S, Zheng DL, Wang YD, Huang JH, Liang XQ, Liang MK. Exploring the antidepressant mechanisms of Guipi pill: A focus on gut-brain axis and immunity modulation. World J Psychiatry 2026; 16(6): 114553
URL: https://www.wjgnet.com/2220-3206/full/v16/i6/114553.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i6.114553

Zhong J, Chen W, Li S, Zheng DL, Wang YD, Huang JH, Liang XQ, Liang MK. Exploring the antidepressant mechanisms of Guipi pill: A focus on gut-brain axis and immunity modulation. World J Psychiatry 2026; 16(6): 114553 [DOI: 10.5498/wjp.v16.i6.114553]

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