Alcohol dehydrogenase 4 expression in hepatocellular carcinoma and its association with tumor invasion, survival, and psychological status

doi:10.5498/wjp.v16.i5.117187

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World Journal of Psychiatry

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2220-3206

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. May 19, 2026; 16(5): 117187
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.117187

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Figure 1 Significant differences in tumor size, microvascular invasion, differentiation degree, and 1-year survival rate between alcohol dehydrogenase 4 high/Low expression groups. Tumor size: Tumors were significantly smaller in the alcohol dehydrogenase 4 (ADH4) high expression group. Microvascular invasion: The microvascular invasion positivity rate was more than double in the ADH4 low expression group. Differentiation degree: The proportion of well-differentiated patients was higher in the ADH4 high expression group. Survival rate: The ADH4 high expression group showed a clear 1-year survival advantage. ADH4: Alcohol dehydrogenase 4; MVI: Microvascular invasion.

Citation: Xia T, Liu CL, Zhang JC, Meng P, Ma YB, Huang QK, Li HM, Zhao XY, Wang C, Zhao G, Kong LH. Alcohol dehydrogenase 4 expression in hepatocellular carcinoma and its association with tumor invasion, survival, and psychological status. World J Psychiatry 2026; 16(5): 117187
URL: https://www.wjgnet.com/2220-3206/full/v16/i5/117187.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i5.117187

Xia T, Liu CL, Zhang JC, Meng P, Ma YB, Huang QK, Li HM, Zhao XY, Wang C, Zhao G, Kong LH. Alcohol dehydrogenase 4 expression in hepatocellular carcinoma and its association with tumor invasion, survival, and psychological status. World J Psychiatry 2026; 16(5): 117187 [DOI: 10.5498/wjp.v16.i5.117187]

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