Alcohol dehydrogenase 4 expression in hepatocellular carcinoma and its association with tumor invasion, survival, and psychological status

doi:10.5498/wjp.v16.i5.117187

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World Journal of Psychiatry

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2220-3206

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Psychiatry. May 19, 2026; 16(5): 117187
Published online May 19, 2026. doi: 10.5498/wjp.v16.i5.117187

Table 2 Cox regression analysis of alcohol dehydrogenase 4 expression and survival prognosis

Factor	Univariate HR (95%CI)	Multivariate HR (95%CI)
Alcohol dehydrogenase 4 low expression	0.402 (0.268-0.603)	0.486 (0.305-0.775)
Large tumor size	2.135 (1.426-3.192)	1.768 (1.135-2.750)
Microvascular invasion positive	2.568 (1.734-3.797)	2.047 (1.315-3.186)

Alcohol dehydrogenase 4 low expression is an independent poor prognostic factor. HR: Hazard ratio.

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Citation: Xia T, Liu CL, Zhang JC, Meng P, Ma YB, Huang QK, Li HM, Zhao XY, Wang C, Zhao G, Kong LH. Alcohol dehydrogenase 4 expression in hepatocellular carcinoma and its association with tumor invasion, survival, and psychological status. World J Psychiatry 2026; 16(5): 117187
URL: https://www.wjgnet.com/2220-3206/full/v16/i5/117187.htm
DOI: https://dx.doi.org/10.5498/wjp.v16.i5.117187

Xia T, Liu CL, Zhang JC, Meng P, Ma YB, Huang QK, Li HM, Zhao XY, Wang C, Zhao G, Kong LH. Alcohol dehydrogenase 4 expression in hepatocellular carcinoma and its association with tumor invasion, survival, and psychological status. World J Psychiatry 2026; 16(5): 117187 [DOI: 10.5498/wjp.v16.i5.117187]

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